作者: Guillaume Tetreau , Renaud Stalinski , Jean-Philippe David , Laurence Després
DOI: 10.1002/ARCH.21076
关键词:
摘要: The bioinsecticide Bacillus thuringiensis var. israelensis (Bti) is increasingly used worldwide for mosquito control. Although no established resistance to Bti has been described in the field so far, a resistant Aedes aegypti strain (LiTOX strain) was selected laboratory using field-collected leaf litter containing toxins. This exhibits moderate level Bti, but high individual Cry As contains four different toxins, generalist mechanisms affecting tolerance toxins were expected strain. In present work, we show that an increase of various gut proteolytic activities including trypsins, leucine-aminopeptidases, and carboxypeptidase A activities. These elevated resulted faster activation Cry4Aa protoxins while Cry4Ba or Cry11Aa not affected. results suggest changes may contribute mosquitoes together with other mechanisms.