Tcf4 can specifically recognize beta-catenin using alternative conformations.

作者: Thomas A. Graham , Denise M. Ferkey , Feng Mao , David Kimelman , Wenqing Xu

DOI: 10.1038/NSB718

关键词:

摘要: … to β-catenin via two conserved lysines in β-catenin (called the charged 'buttons'). Here we report the crystal structure of a β-catenin–Tcf4 … that Tcf4 docks specifically to β-catenin using …

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