Screening of HIV infection: role of molecular and immunological assays.

摘要: Due to technical improvements and new developments of immunological assays, the reliability serological laboratory diagnosis HIV infection has improved considerably residual risk, due diagnostic window for transfusion-transmitted HIV, been reduced significantly. Through addition nucleic acid amplification tests (NAT) blood donor screening, risk can de further decreased by up 50%, depending on sensitivity NAT protocol whether individual or pooled donations are screened. In-house commercially available have implemented in banks as only multiplexed hepatitis B C virus assays. As an alternative separate antigen antibody combined fourth-generation assays developed 1997, achieved a high degree specificity. Thus, they replace stand-alone third-generation While used routine diagnostics infecti...