SCORE Study Report #11
作者： Clement K. Chan , Michael S. Ip , Paul C. VanVeldhuisen , Neal L. Oden , Ingrid U. Scott
DOI: 10.1016/J.OPHTHA.2010.11.020
关键词:
摘要: Purpose To investigate in The Standard Care versus COrticosteroid for REtinal Vein Occlusion (SCORE) Study: (1) incidences of neovascular events and retinal capillary nonperfusion (abbreviated as "nonperfusion"), their relationship with treatment groups; (2) by status; (3) pertinent baseline factors potential risk events. Design Two multicenter, randomized clinical trials, 1 evaluating participants central vein occlusion (CRVO) the other branch (BRVO). Participants At 36 months, data were available 81 CRVO 128 BRVO. Intervention care (observation or grid photocoagulation) 4 mg intravitreal triamcinolone. Main Outcome Measures Neovascularization iris (NVI), glaucoma (NVG), disc neovascularization (NVD/NVE), preretinal vitreous hemorrhage (PRH/VH), nonperfusion. Results cumulative 36-month BRVO eyes, respectively, 8.5% 2.4% NVI NVG; 8.8% 7.6% NVD/NVE PRH/VH. There no differences when comparing 3 groups within diseases. For at 16.6% eyes ≥5.5 areas 4.0% P = 0.0003); 14.6% developed ( Conclusions In SCORE Study, triamcinolone was not associated lower status compared observation photocoagulation. Cumulative most significantly higher nonperfused than perfused eyes. Greater increased but possibly owing to obscuration details caused dense Increased noted below historical threshold 10 occlusion. Financial Disclosure(s) authors have proprietary commercial interest any materials discussed this article.
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