Core Pluripotency Factors Directly Regulate Metabolism in Embryonic Stem Cell to Maintain Pluripotency.

Oscar Yanes, Julie Clark, Diana M Wong, Gary J Patti, Antonio Sánchez-Ruiz, H Paul Benton, Sunia A Trauger, Caroline Desponts, Sheng Ding, Gary Siuzdak, Metabolic oxidation regulates embryonic stem cell differentiation Nature Chemical Biology. ,vol. 6, pp. 411- 417 ,(2010) , 10.1038/NCHEMBIO.364

Daniel Esch, Juha Vahokoski, Matthew R. Groves, Vivian Pogenberg, Vlad Cojocaru, Hermann vom Bruch, Dong Han, Hannes C. A. Drexler, Marcos J. Araúzo-Bravo, Calista K. L. Ng, Ralf Jauch, Matthias Wilmanns, Hans R. Schöler, A unique Oct4 interface is crucial for reprogramming to pluripotency Nature Cell Biology. ,vol. 15, pp. 295- 301 ,(2013) , 10.1038/NCB2680

Heather R. Christofk, Matthew G. Vander Heiden, Marian H. Harris, Arvind Ramanathan, Robert E. Gerszten, Ru Wei, Mark D. Fleming, Stuart L. Schreiber, Lewis C. Cantley, The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth Nature. ,vol. 452, pp. 230- 233 ,(2008) , 10.1038/NATURE06734

Clifford D.L. Folmes, Timothy J. Nelson, Almudena Martinez-Fernandez, D. Kent Arrell, Jelena Zlatkovic Lindor, Petras P. Dzeja, Yasuhiro Ikeda, Carmen Perez-Terzic, Andre Terzic, Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming Cell Metabolism. ,vol. 14, pp. 264- 271 ,(2011) , 10.1016/J.CMET.2011.06.011

Sandra Varum, Ana S. Rodrigues, Michelle B. Moura, Olga Momcilovic, Charles A. Easley, João Ramalho-Santos, Bennett Van Houten, Gerald Schatten, Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated Counterparts PLoS ONE. ,vol. 6, pp. e20914- ,(2011) , 10.1371/JOURNAL.PONE.0020914

Alessandro Prigione, Beatrix Fauler, Rudi Lurz, Hans Lehrach, James Adjaye, The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells. Stem Cells. ,vol. 28, pp. 721- 733 ,(2010) , 10.1002/STEM.404

Alexander Marson, Stuart S. Levine, Megan F. Cole, Garrett M. Frampton, Tobias Brambrink, Sarah Johnstone, Matthew G. Guenther, Wendy K. Johnston, Marius Wernig, Jamie Newman, J. Mauro Calabrese, Lucas M. Dennis, Thomas L. Volkert, Sumeet Gupta, Jennifer Love, Nancy Hannett, Phillip A. Sharp, David P. Bartel, Rudolf Jaenisch, Richard A. Young, Connecting microrna genes to the core transcriptional regulatory circuitry of embryonic stem cells Cell. ,vol. 134, pp. 521- 533 ,(2009) , 10.1016/J.CELL.2008.07.020

Lyle Armstrong, Katarzyna Tilgner, Gabriele Saretzki, Stuart P. Atkinson, Miodrag Stojkovic, Ruben Moreno, Stefan Przyborski, Majlinda Lako, Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells. Stem Cells. ,vol. 28, pp. 661- 673 ,(2010) , 10.1002/STEM.307

Hyonchol Jang, Tae Wan Kim, Sungho Yoon, Soo-Youn Choi, Tae-Wook Kang, Seon-Young Kim, Yoo-Wook Kwon, Eun-Jung Cho, Hong-Duk Youn, O -GlcNAc Regulates Pluripotency and Reprogramming by Directly Acting on Core Components of the Pluripotency Network Cell Stem Cell. ,vol. 11, pp. 62- 74 ,(2012) , 10.1016/J.STEM.2012.03.001

Jungwoon Lee, Hye Kyoung Kim, Yong-Mahn Han, Jungho Kim, None, Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription. The International Journal of Biochemistry & Cell Biology. ,vol. 40, pp. 1043- 1054 ,(2008) , 10.1016/J.BIOCEL.2007.11.009