Dihydroartemisinin-Stimulated Hyperplasia of Rat Lung Smooth Muscles
作者： Saravanan
DOI: 10.3844/AJASSP.2012.177.179
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摘要: Problem statement: Dihydroartemisinin was shown to produce two types of inhibitory effects on the cardiac muscles rats. It also stimulate haemopoiesis in lungs, liver, spleen, intestine and kidney This study attempted find out nature effect oral dihydroartemisinin lungs Wistar albino Approach: The tissues wistar rats were investigated with five doses (DHA) administered for 5 days by intubation. tested 1 mg kg-1, a repeated dose 1, 2, 60 80 kg-1 DHA. Results: Histopathological examination tissue micrographs treated showed that comparism those controls, DHA had no adverse but rather produced direct stimulatory smooth lungs. stimulation caused hyperplasia these which observable histologically These dose, repetition time dependent. Conclusion: growth hormone-like suggest enhanced functioning capacity DHA-treated results has possible respiration enhancement effects.
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