Neuronal network of panic disorder: the role of the neuropeptide cholecystokinin.

作者: P. Zwanzger , K. Domschke , J. Bradwejn

DOI: 10.1002/DA.21919

关键词:

摘要: … suggests that the neuropeptide cholecystokinin (CCK) might … CCK interacts with several anxiety-relevant neurotransmitters … In humans, administration of CCK-4 reliably provokes panic …

参考文章(171)
Peter Zwanzger, Daniela Eser, Nikolas Völkel, Thomas C. Baghai, Hans-Jürgen Möller, Rainer Rupprecht, Frank Padberg, Effects of repetitive transcranial magnetic stimulation (rTMS) on panic attacks induced by cholecystokinin-tetrapeptide (CCK-4). The International Journal of Neuropsychopharmacology. ,vol. 10, pp. 285- 289 ,(2007) , 10.1017/S146114570600695X
Miklo´s Palkovits, Jo´zsef Z. Kiss, Margery C. Beinfeld, Michael J. Brownstein, Cholecystokinin in the hypothalamo-hypophyseal system. Brain Research. ,vol. 299, pp. 186- 189 ,(1984) , 10.1016/0006-8993(84)90806-0
Rainer Rupprecht, Gerhard Rammes, Daniela Eser, Thomas C. Baghai, Cornelius Schüle, Caroline Nothdurfter, Thomas Troxler, Conrad Gentsch, Hans O. Kalkman, Frederique Chaperon, Veska Uzunov, Kevin H. McAllister, Valerie Bertaina-Anglade, Christophe Drieu La Rochelle, Dietrich Tuerck, Annette Floesser, Beate Kiese, Michael Schumacher, Rainer Landgraf, Florian Holsboer, Klaus Kucher, Translocator Protein (18 kD) as Target for Anxiolytics Without Benzodiazepine-Like Side Effects Science. ,vol. 325, pp. 490- 493 ,(2009) , 10.1126/SCIENCE.1175055
Hyunyoung Kim, Wei-Whan Whang, Hyun-Taek Kim, Kwang-Ho Pyun, Sun-Young Cho, Dae-Hyun Hahm, Hye-Jung Lee, Insop Shim, Expression of neuropeptide Y and cholecystokinin in the rat brain by chronic mild stress. Brain Research. ,vol. 983, pp. 201- 208 ,(2003) , 10.1016/S0006-8993(03)03087-7
Santiago Ballaz, Ana Barber, Ana Fortuño, Joaquín Del Río, Mercedes Martín-Martínez, Isabel Gómez-Monterrey, Rosario Herranz, Rosario González-Muñiz, Maria-Teresa García-López, Pharmacological evaluation of IQM-95,333, a highly selective CCKA receptor antagonist with anxiolytic-like activity in animal models British Journal of Pharmacology. ,vol. 121, pp. 759- 767 ,(1997) , 10.1038/SJ.BJP.0701186
Michael Kellner, Christoph Muhtz, Kristina Stark, Alexander Yassouridis, Josef Arlt, Klaus Wiedemann, Effects of a metabotropic glutamate(2/3) receptor agonist (LY544344/LY354740) on panic anxiety induced by cholecystokinin tetrapeptide in healthy humans: preliminary results. Psychopharmacology. ,vol. 179, pp. 310- 315 ,(2005) , 10.1007/S00213-004-2025-1
Yukiko Yamamoto, Jotaro Akiyoshi, Akio Kiyota, Satomi Katsuragi, Takashi Tsutsumi, Koichi Isogawa, Haruo Nagayama, Increased anxiety behavior in OLETF rats without cholecystokinin-A receptor. Brain Research Bulletin. ,vol. 53, pp. 789- 792 ,(2000) , 10.1016/S0361-9230(00)00407-X