Über Steroide. 118. Mitteilung. Ein neues Verfahren zur Herstellung von Steroiden mit 11β-Hydroxylgruppe. I. Versuche an Verbindungen der Spirostanreihe

作者: J. Schmidlin , A. Wettstein

DOI: 10.1002/HLCA.19530360604

关键词:

摘要: A simple five-step conversion of 12-ketosteroids into 11 β-hydroxy compounds (and also 11-ketones) through β, 12 β-epoxides is described. The process can be accomplished with high yields, as it shown in the present paper dealing application to hecogenin acetate.

参考文章(3)
ROSE. ANTONUCCI, SEYMOUR. BERNSTEIN, MILTON. HELLER, ROBERT. LENHARD, RUDDY. LITTELL, JAMES H. WILLIAMS, STEROIDAL CYCLIC KETALS. III.1, 2 HYDROCORTISONE AND RELATED CORTICOIDS Journal of Organic Chemistry. ,vol. 18, pp. 70- 82 ,(1953) , 10.1021/JO01129A013