Vitamin D insufficiency is associated with higher carotid intima-media thickness in psoriatic patients.

摘要: Psoriasis has been associated with vitamin D insufficiency and cardiovascular risk factors. Reports show that serum 25-hydroxyvitamin (25-OHD) levels are inversely chronic inflammatory systemic diseases, factors outcomes. To analyze the association between subclinical carotid atherosclerosis (maximal intima-media thickness (MIMT)) in psoriasis patients controls. MIMT was compared were analyzed. This a case-control study 44 psoriatic without arthritis from Dermatology outpatient clinic Granada (Spain) Confounding related to 25-OHD also significantly lower than control group (29.20 vs. 38.00 ng/mL p<0.0001) significant negative correlation found (rs = −0.678, patients. No healthy remained after adjusting for confounders. Serum (p 0.003) atheromatous plaque (22.38 ± 10.23 ng/mL) those (31.74 8.62 ng/mL). Patients longer history of presented higher controls (638.70 76.21 vs 594.67 80.20 μm; p 0.026 ≥6 yrs psoriasis). In patients, selected confounding The increases psoriasis, regardless patient’s age.