Comparing regional brain atrophy in mild cognitive impairment and Alzheimer’s disease

摘要: SUMMARY Neuroimaging has assumed an active role in the diagnosis of Alzheimer’s disease (AD) and other dementias. Structural MRI can estimate changes specific brain structures relative to normal pathological aging such as volume, cortical thickness gray matter density. Several different structural methods be used identify neuropathology point early atrophy medial temporal lobe patients with AD amnestic mild cognitive impairment, especially entorhinal cortex hippocampus. These alterations were also considered evidence for neurodegeneration, even preclinical AD. However, evaluation areas ventricular enlargement precuneus may help diagnosis, stages disease. Currently, neuroimaging is excellent tool increasing diagnostic accuracy, but does not substitute a careful clinical neuropsychological evaluation. In this article, our objective gather in...