Targeting Inducible Chemotherapy Resistance Mechanisms in Colon Cancer
作者： David Ljungman , James C. Cusack
DOI: 10.1385/1-59259-893-5:209
关键词:
摘要: Resistance toward chemotherapy remains one of the principle obstacles to effective treatment malignancies. As our knowledge mechanisms involved in cancer biology expands, new molecular targets emerge. This chapter aims overview major resistance mechanisms, order identify potential appropriate for developmental therapeutics. An emphasis on role transcription factor NF-κB colorectal is presented as an example how targeted therapies may advance from bench bedside.
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