The rate of collagen maturation in rat and human skin.

作者: Mady Le Lous , Jean-Claude Allain , Lola Cohen-Solal , Pierre Maroteaux

DOI: 10.3109/03008208209160271

关键词:

摘要: Hydrothermal Isometric Tension (HIT) relaxation was observed at the boiling point in rat, cat and human skin samples of different ages, after raising temperature from 37° to 100°C a rate 1.15°C/min.A Maxwellian nearly zero point. A given velocity constant characterized tissue whether experiments were performed under pressure or tensile stress. However, decreased as function age for all three species during period studied. Moreover, same cats aged 1 5 years, rats 9 28 months children birth 10 years.We propose model, based on well known rubber-elastic properties denatured collagen network. In this model (1) HIT decreases an exponential time bond scission along polymeric chains; (2) process is proportional...

参考文章(22)
A. J. Bailey, S. P. Robins, G. Balian, Biological significance of the intermolecular crosslinks of collagen. Nature. ,vol. 251, pp. 105- 109 ,(1974) , 10.1038/251105A0
S L Schnider, R R Kohn, Effects of age and diabetes mellitus on the solubility and nonenzymatic glucosylation of human skin collagen. Journal of Clinical Investigation. ,vol. 67, pp. 1630- 1635 ,(1981) , 10.1172/JCI110198
Norman M. Wiederhorn, Gerald V. Reardon, Studies concerned with the structure of collagen. II. Stress-strain behavior of thermally contracted collagen Journal of Polymer Science. ,vol. 9, pp. 315- 325 ,(1952) , 10.1002/POL.1952.120090404
P. J. Flory, O. K. Spurr, Melting Equilibrium for Collagen Fibers under Stress. Elasticity in the Amorphous State1 Journal of the American Chemical Society. ,vol. 83, pp. 1308- 1316 ,(1961) , 10.1021/JA01467A013
Paul J Flory, Robert R Garrett, None, Phase Transitions in Collagen and Gelatin Systems1 Journal of the American Chemical Society. ,vol. 80, pp. 4836- 4845 ,(1958) , 10.1021/JA01551A020
A Le Pape, J P Muh, A J Bailey, Characterization of N-glycosylated type I collagen in streptozotocin-induced diabetes Biochemical Journal. ,vol. 197, pp. 405- 412 ,(1981) , 10.1042/BJ1970405
J.C. Allain, M. Le Lous, S. Bazin, A.J. Bailey, A. Delaunay, Isometric tension developed during heating of collagenous tissues Biochimica et Biophysica Acta (BBA) - Protein Structure. ,vol. 533, pp. 147- 155 ,(1978) , 10.1016/0005-2795(78)90558-5