Molecular imaging and cancer gene therapy

摘要: Gene therapy is known as one of the most advanced approaches for therapeutic prospects ranging from tackling genetic diseases to combating cancer. In this approach, different viral and nonviral vector systems such retrovirus, lentivirus, plasmid transposon have been designed employed. These are target genes in various tissues cells tumor cells. Therefore, detection vectors containing monitoring response treatment main issues that commonly faced by researchers. Imaging techniques critical guiding physicians more accurate precise diagnosis cancer patients phases malignancies. positron emission tomography (PET) single-photon computed (SPECT) non-invasive powerful tools distribution transgene expression over time assessing who received genes. Here, we discuss recent advances gene molecular well imaging utilized detect therapeutics monitor patients’ these therapies worldwide, particularly Iranian Academic Medical Centers Hospitals.