Circulating microRNA-133, microRNA-17 and microRNA-25 in Serum and Its Potential Diagnostic Value in Gastric Cancer
作者： Parisa ZiaSarabi , Saba Sorayayi , AmirReza Hesari , Faezeh Ghasemi
DOI: 10.1002/JCB.28503
关键词:
摘要: Gastric cancer is one of the most common malignancies in world and considered as lethal gastrointestinal cancer. microRNAs (miRNAs) can be very important detecting a disease at an early stage. The aim this study was to investigate microRNA-17 (miR-17), miR-25, miR-133b serum gastric subjects. Serum samples were obtained from 120 cancers 102 healthy We evaluated expression levels miR-17, miR-25 by quantitative real-time polymerase chain reaction. Our results showed that patients with cancer, level miR-17 significantly increased compared control group (P < 0.5), while decreased patient groups cases 0.5). It seems miRNAs Iranian similar other populations. These findings suggested could introduced potential diagnostic candidates for detection
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