Epidemiology of Gastric Cancer

摘要: Gastric cancer is the third leading cause of cancer-related death worldwide. Despite a decrease in its incidence some regions world, gastric still poses major clinical challenge because most cases are diagnosed an advanced stage, with poor prognosis and limited treatment options. The common causes Helicobacter pylori infection (proven), Epstein-Barr virus (suspected), familial. Major predisposing factors include high salt intake, smoking, familial genetic component. Primary prevention (i.e., H. eradication) increasingly recommended. growing understanding both phenotypic alterations molecular mechanisms occurring during carcinogenesis, no reliable biomarkers available as yet for use secondary strategies.