Alcohol consumption, smoking and risk of gastric cancer: case-control study from Moscow, Russia.

摘要: Objectives: To examine the risk of gastric cancer associated with alcohol consumption and smoking in men women Moscow, Russia. Materials methods: A case-control study which includes 448 cases 610 controls was conducted. Cases consisted patients newly diagnosed histologically confirmed cancer. Controls were admitted during period to hospital diagnoses other than and/or gastrointestinal diseases. Information on demographic variables, smoking, diet collected from all subjects. Venous blood drawn 361 441 controls. serological test for Helicobacter pylori immunoglobulin G performed. Results: Alcohol consumption, particularly vodka found increase In effect hard liquor drinking stronger cardia (OR = 3.4, CI 1.2–10.2), while sites 1.5, 1.0–2.3). Smoking increased developing men, but not women. a dose-response relationship between mean number cigarettes smoked per day (p 0.03), pack-years 0.01) duration 0.08) observed. Further statistical analysis revealed interactions H. infection status. Conclusions: The findings further support role etiology