Obesity and the risk of early and late mortality after coronary artery bypass graft surgery

摘要: Abstract Background Obesity is often considered to be a significant risk factor for postoperative mortality when selecting candidates coronary artery bypass grafting (CABG). Methods We included all patients undergoing first isolated CABG at the Karolinska Hospital in Stockholm, Sweden, between 1980 and 1995 (n = 6728). Patients were categorized on basis of body mass index (BMI): non-overweight (BMI 2 ), overweight (25 kg/m ≤ BMI obese ≥30 ). Multivariate Cox regression was used assess re-operation bleeding, deep sternal wound infection, early (≤30 days) late (≤5 years) rates. Results The average length follow-up 6.5 years. There 252 re-operations 53 infections, 628 deaths. who had significantly lower bleeding (risk ratio [RR], 0.32; 95% CI, 0.19–0.53), but greater infection (RR, 2.66; 1.21–5.88) compared with not overweight. However, experienced similar 30-day 0.65; 0.34–1.27), 1-year 0.56; 0.29–1.10), 5-year rates 0.91; 0.66–1.25). consistent those obese. Conclusion are after overweight, although they appear have infection. Therefore, obesity per se contraindication CABG.