Weight change after myocardial infarction--the Enhancing Recovery in Coronary Heart Disease patients (ENRICHD) experience.

摘要: Background The relationship of changes in weight to outcomes patients after myocardial infarction (MI) is controversial. Methods From the ENRICHD trial data, we assessed change, and associations baseline change at follow-up with interactions between psychosocial factors. Results At baseline, 73.6% (n = 1706) were overweight or obese; 134 had body mass index ≥40. Underweight more likely die have nonfatal recurrent MI. After controlling for covariates, obese similar normal-weight patients. Eighteen percent gained >5%, 27% lost 55% ≤5% weight. Compared loss ≤5%, risk death (adjusted hazard ratio 1.74, P .01) cardiovascular (hazard 1.79, .04) increased >5%. propensity matching, >5% remained as a significant factor death. There was no interaction depression and/or social support follow-up. Weight not associated MI hospitalizations. Conclusions A large proportion lose gain an association obesity lower mortality modulated by comorbidities. worse related support.