Peripheral intravenous feeding with isotonic amino acid solutions.

作者: G.L. Blackburn , J.P. Flatt , G.H.A. Clowes , T.E. O'Donnell

DOI: 10.1016/0002-9610(73)90080-9

关键词:

摘要: Abstract Nitrogen balance was studied in ten patients receiving peripheral solutions of the following: (1) 5 per cent dextrose and water; (2) 3 amino acids; (3) acids alone. Significant improvement nitrogen observed when were administered without glucose. This associated with lower insulin glucose levels elevated free fatty ketones. A new concept on which to base parenteral protein-sparing therapy is presented.

参考文章(20)
S. B. Jørgensen, J. M. Kinney, J. H. Duke, C. L. Long, J. R. Broell, Contribution of protein to caloric expenditure following injury. Surgery. ,vol. 68, pp. 168- 174 ,(1970)
U. Gottstein, W. M�ller, W. Berghoff, H. G�rtner, K. Held, Zur Utilisation von nicht-veresterten Fettsäuren und Ketonkörpern im Gehirn des Menschen Journal of Molecular Medicine. ,vol. 49, pp. 406- 411 ,(1971) , 10.1007/BF01484996
Seymour I. Schwartz, Principles of Surgery ,(1969)
Vincent P. Dole, Hans Meinertz, Microdetermination of long-chain fatty acids in plasma and tissues. Journal of Biological Chemistry. ,vol. 235, pp. 2595- 2599 ,(1960) , 10.1016/S0021-9258(19)76920-8
P.J. Randle, P.B. Garland, C.N. Hales, E.A. Newsholme, The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. The Lancet. ,vol. 281, pp. 785- 789 ,(1963) , 10.1016/S0140-6736(63)91500-9
Marvin S. Kaplan, High Caloric Glucose-Nitrogen Infusions Archives of Surgery. ,vol. 99, pp. 567- 571 ,(1969) , 10.1001/ARCHSURG.1969.01340170019005
Oliver E. Owen, Philip Felig, Alfred P. Morgan, John Wahren, George F. Cahill, Liver and kidney metabolism during prolonged starvation Journal of Clinical Investigation. ,vol. 48, pp. 574- 583 ,(1969) , 10.1172/JCI106016
Louis M. Sherwood, Edith E. Parris, Roger H. Unger, Glucagon Physiology and Pathophysiology The New England Journal of Medicine. ,vol. 285, pp. 443- 449 ,(1971) , 10.1056/NEJM197108192850806
Bela Issekutz, Walter M. Bortz, Harvey I. Miller, Pavle Paul, Turnover rate of plasma FFA in humans and in dogs Metabolism-clinical and Experimental. ,vol. 16, pp. 1001- 1009 ,(1967) , 10.1016/0026-0495(67)90093-5