Phrenic nerve dysfunction after heart-lung and lung transplantation.

摘要: Background Phrenic nerve dysfunction (PND) is a well-known complication after cardiac surgery, but reports on its incidence and consequences heart–lung lung transplantation are scarce. Methods The (ventilator days intensive-care unit length of stay [ICU LOS]) PND were studied by retrospective chart review 27 (HLTx) 111 (LTx) transplantations performed from July 1991 to June 2001 at the Leuven University Hospital, Leuven, Belgium. On clinical suspicion diaphragmatic dysfunction, conduction studies performed, which completed with needle electromyogram (EMG) diaphragm when study was non-conclusive. Results The in 21 evaluable HLTx recipients 42.8% (9 patients), resulting significantly more ventilator for patients (37.6 ± 36.3 vs 5.3 3 days; p < 0.05) prolonged ICU LOS (46.8 33 9.8 4.9 0.05). In 97 LTx patients, 9.3% patients) developed PND. This resulted group (30.6 14.8 non-PND 7.9 days. longer (PND 37.8 18.7 12.1 17.8 Needle EMG revealed denervation 1 5 patients. sustaining tracheostomies (44.4% 4.5% 0.005). Eight 9 had sequential single-lung transplantation. Conclusions PND represents an important problem has considerable influence both number resource utilization.