Differences of E-cadherin expression levels and patterns in human lung cancer
作者： M. Böhm , B. Totzeck , I. Wieland
DOI: 10.1007/BF01715136
关键词:
摘要: Fifty-two lung carcinomas obtained at surgical resection were examined by immunofluorescence for their expression levels and patterns of the calciumdependent intercellular adhesion molecule E-cadherin. In well-differentiated squamous cell adenocarcinomas E-cadherin was confined to lateral border, similar level pattern normal tissue. The reduced spotty or diffuse in moderately poorly differentiated small lung. Also, most metastases resected had a an altered expression. contrast, no such correlation found This indicates that different cellular mechanisms are responsible progression versus
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