作者: Ivette F Emery , Chiara Battelli , Paul L Auclair , Kathleen Carrier , Daniel M Hayes
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摘要: Background In Non-small cell lung cancer (NSCLC), an overactive epidermal growth factor receptor (EGFR) pathway is a component of the malignant phenotype. Two tyrosine kinase inhibitors (TKIs) EGFR, gefinitib and erlotinib, have been used with variable benefit.