摘要: This article describes the data on isotopic effects of deuterium in various biological objects as cells methylotrophic, chemoheterotrophic, photoorganotrophic microorganisms, green algae well animal cells. It was demonstrated that increased content water leads to physiological, morphological and cytology alterations cell, also renders negative influence cellular metabolism, while depleted (DDW) with decreased 20–30 % exerts beneficial organism. The maximum kinetic effect measured at ordinary temperatures chemical reactions leading rupture bonds involving hydrogen lies range k H /k D = 6–8 for C – versus , N O - . By IR-spectroscopy method samples varying were investigated. Key words: deuterium, heavy water, effects, systems, IR-spectroscopy.
iiste.org参考文章(52)
Haulica I, Nastasa, Bild W, Stefanescu I, Lupuşoru C, Iliescu R, Titescu G, Research concerning the radioprotective and immunostimulating effects of deuterium-depleted water. Romanian journal of physiology : physiological sciences / [Academia de Stiinte Medicale]. ,vol. 36, pp. 205- 218 ,(1999)
E E Antoshina, D G Zaridze, L S Trukhanova, A I Grigor'ev, V S Turusov, T G Gor'kova, Iu E siniak, [Low-deuterium water effect on transplantable tumors]. Voprosy onkologii. ,vol. 51, pp. 99- 102 ,(2005)
G. E. Walrafen, Raman and Infrared Spectral Investigations of Water Structure The Physics and Physical Chemistry of Water. pp. 151- 214 ,(1972) , 10.1007/978-1-4684-8334-5_5
Ignat Ignatov, Oleg Mosin, Biosynthesis of photochrome transmembrane protein bacteriorhodopsin of Halobacterium halobium labeled with deuterium at aromatic amino acids residues of 2,3,4,5,6-2H5]Phe, [3,5-2H2]Tyr and [2,4,5,6,7 -2H5]Trp chemistry and materials research. ,vol. 6, pp. 38- 49 ,(2014)
Ignat Ignatov, Oleg Mosin, Photochrome Transmembrane Protein Bacteriorhodopsin from Purple Membranes of Halobacterium Halobium in Nano- and Biotechnologies Journal of Medicine, Physiology and Biophysics. ,vol. 4, pp. 81- 99 ,(2014)
I. Ignatov, Mosin, O. V., Origin of Life and Living Matter in Hot Mineral Water Advances in Physics Theories and Applications. ,vol. 39, pp. 1- 22 ,(2015)
Ignat Ignatov, Oleg Mosin, The Strain of Facultative Methylotrophic Bacterium ?revibacterium Methylicum 5662 with RuMP Cycle of Carbon Assimilation for Biosynthesis of Deuterium Labeled Phenylalanine Journal of Medicine, Physiology and Biophysics. ,vol. 5, pp. 108- 128 ,(2014)
Ignat Ignatov, Oleg Mosin, Studying of the Biosynthesis of 2H-Labeled Inosine by a Gram-positive Chemoheterotrophic Bacterium Bacillus Subtilis B-3157 on Heavy Water (2H2O) Medium Chemical and Process Engineering Research. ,vol. 15, pp. 32- 45 ,(2013)
Ignat Ignatov, Oleg Mosin, Chemoheterotrophic Bacterium Bacillus Subtilis B-3157. Microbiological Preparation of Deuterium Labeled Purine Ribonucleoside Inosine from Bacillus Subtilis B-3157 Journal of Medicine, Physiology and Biophysics. ,vol. 8, pp. 22- 45 ,(2014)
Jean-Joseph Max, Camille Chapados, Isotope effects in liquid water by infrared spectroscopy. III. H2O and D2O spectra from 6000to0cm−1 Journal of Chemical Physics. ,vol. 131, pp. 184505- ,(2009) , 10.1063/1.3258646