Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway.

作者: S.-Y. Shin , O. Rath , S.-M. Choo , F. Fee , B. McFerran

DOI: 10.1242/JCS.036319

关键词:

摘要: … on an experimentally validated mathematical model. We show that the negative-feedback loop from … loop is deleted, we modified the mathematical model so that Raf-1 activity could be …

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