Plants with increased hyaluronan production

作者: Claus Frohberg , Bernd Essigmann

DOI:

关键词:

摘要: The present invention relates to plant cells and plants which synthesize an increased amount of hyaluronan, methods for preparing such plants, also hyaluronan with the aid these or plants. Here, genetically modified according have synthase activity additionally glutamine:fructose 6-phosphate amidotransferase (GFAT) compared wild-type furthermore use having synthesis food feedstuff containing hyaluronan.

参考文章(13)
Claus Frohberg, Rainhard Koch, Process and means for the production of hyaluronan ,(2004)
Kanwarpal S. Dhugga, Scott E. Nichols, Patricia Lynne Fallis, Tie Wang, Benjamin A. Bowen, Xun Wang, Plant glutamine: fructose-6-phosphate amidotransferase nucleic acids ,(1999)
Claus Frohberg, Rainhard Koch, Methods and means for producing hyaluronan ,(2005)
Hiroaki Kitazawa, Shigeo Shibatani, Atsushi Sogabe, Plant producing hyaluronic acid ,(2006)
Paul H. Weigel, Kshama Kumari, Paul L. DeAngelis, Methods of producing hyaluronic acid using a recombinant hyaluronan synthase gene ,(2005)
Michael V. Graves, Dwight E. Burbank, Robyn Roth, John Heuser, Paul L. DeAngelis, James L. Van Etten, Hyaluronan Synthesis in Virus PBCV-1-Infected Chlorella-like Green Algae Virology. ,vol. 257, pp. 15- 23 ,(1999) , 10.1006/VIRO.1999.9628
H Horvath, J Huang, O Wong, E Kohl, T Okita, CG Kannangara, D. von Wettstein, None, The production of recombinant proteins in transgenic barley grains. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 97, pp. 1914- 1919 ,(2000) , 10.1073/PNAS.030527497
Takashi Yamada, Takeru Kawasaki, Microbial synthesis of hyaluronan and chitin: New approaches Journal of Bioscience and Bioengineering. ,vol. 99, pp. 521- 528 ,(2005) , 10.1263/JBB.99.521