Antiparasitic effects of Sophora flavescens root extracts on the ciliate, Cryptocaryon irritans

摘要: Abstract The antiparasitic effects of 59 water- and methanol-soluble herbal extracts were screened for their potential to inhibit cilia-based motility the protozoan, Cryptocaryon irritans , during its infective (theront) phase. Both five herbs had strong activity. In vitro results confirmed in vivo oral-challenge trials with red sea bream, Pagrus major . water-soluble Sophora flavescens extract most potent anti- C. For a short-term trial, number parasites groups treated 5 or 10 g·kg − 1 feed S. was significantly lower than that control group reduced by more 40% compared control. an 80 day oral challenge trial P. all fish (5 g·kg feed) survived throughout experimental period, which contrasts 100% mortality seen group. Furthermore, effect previously infected also evaluated 4 day trial. this 30% These suggest could be effective controlling infections.