作者: Elena Mancuso , Oana Bretcanu , Martyn Marshall , Kenneth W. Dalgarno
DOI: 10.1016/J.CERAMINT.2017.06.146
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摘要: Three novel glass compositions, identified as NCL2 (SiO2-based), NCL4 (B2O3-based) and NCL7 along with apatite-wollastonite (AW) were processed to form sintered dense pellets, subsequently evaluated for their in vitro bioactive potential, resulting physico-chemical properties degradation rate. Microstructural analysis showed the carbonated hydroxyapatite (HCA) precipitate morphology following SBF testing be composition-dependent. AW formulation exhibited greater HCA precursor formation than NCL4-derived pellets. Moreover, borate-based samples highest biodegradation rate; silicate-derived structures displaying lowest weight loss after immersion. The results of this study suggested that composition has significant influence on apatite-forming ability also rate, indicating possibility customise class materials towards bone repair regeneration process.