Responses of inferior colliculus neurons to sounds presented at different rates in anesthetized albino mouse.

摘要: We recorded extracellular activity from 402 single units located in the inferior colliculus (IC) of barbiturate-anesthetized albino mice. The stimuli were pure tones at characteristic frequency (CF) with durations 10, 40 and 100 ms intensities ranged 5 to 25 dB above unit's minimum threshold (MT). presented different repetition rates (RRs) ranging 0.2 20.0 Hz. At low (5 MT, determined RR 0.5 Hz) great majority exhibited a strong decline their responses when stimulus was increased. About one-half did not respond they stimulated 3.0 This effect even more pronounced for tones. Generally, increase intensity led an high-frequency border RR. Nevertheless, 20-30 some showed no response exceeded 5.0 In many cases band-pass or high-pass duration tuning unit transformed low-pass all-pass rate enough guarantee independence successive presentations stimuli. Responses very small group IC units, however, enhanced Our data have shown that changes radically modify features neural (number spikes, latency, discharge pattern, selectivity). suggest long-lasting inhibitory processes may be induced by IC.