Continuous Luteinizing Hormone Infusion Prevents Atretic Changes of the Follicles During Superovulation in Hamsters

摘要: Superovulation with exogenous gonadotropins has been used widely to study the reproductive events in animals and vitro fertilization embryo transfer human beings. However, details of mechanism superovulation are not yet clearly understood. The present was conducted purified FSH LH preparations. Cyclic hamsters received continuous infusion for 4 days, from estrus proestrus. number ova shed significantly increased by 5 iu FSH/minipump infusion, further plus LH/minipump group. On other hand, atretic follicles decreased (P < 0.01) combined LH, but alone. Among these experimental groups, there no significant difference embryonic development which assessed counting 4-cells more developed embryos on day 3 pregnancy. These data indicated different roles process, because stimulated some small grow presence FSH, rescued undergo atresia.