Genomic evidence of homologous recombination in spring viremia of carp virus: a negatively single stranded RNA virus.

摘要: Abstract A new strain of spring viraemia carp virus, denominated SVCV-265, was isolated from an ornamental common ( Cyprinus carpio ) in Shanghai, China, 2013. The isolate could produce obvious cytopathic effects on EPC cells, while shown to be low virulence for juvenile koi. Complete genome sequencing revealed the SVCV-265 is 11,029 nucleotides length and phylogenetic analysis showed clustered within Asia clade but divergent Chinese A1, A2 BJ0505-2 strains. Previous report indicated that G P gene SVCV shared similar topologies evolutionary trees. In this study, based sequences into Iai subgroup isolates BJ0505-2, which were Iaii group. However, sequence alignment has a close relationship with isolates. Recombination all whole available likely homologous recombination descendants A1 SVCV-265. crossover regions located between 3845–6387 nt 3573–6444 nt respectively. Phylogenetic region further confirmed these findings. This current study describes molecular characterization China first SVCV.