Circulating omentin concentration increases after weight loss
作者： José Moreno-Navarrete , Victoria Catalán , Francisco Ortega , Javier Gómez-Ambrosi , Wifredo Ricart
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摘要: Omentin-1 is a novel adipokine expressed in visceral adipose tissue and negatively associated with insulin resistance obesity. We aimed to study the effects of weight loss-induced improved sensitivity on circulating omentin concentrations. Circulating omentin-1 (ELISA) concentration association metabolic variables was measured 35 obese subjects (18 men, 17 women) before after hypocaloric loss. Baseline concentrations correlated BMI (r = -0.58, p < 0.001), body -0.35, 0.045), fat mass -0.67, leptin -0.7, 0.001) fasting -0.37, 0.03). increased significantly loss (from 44.9 ± 9.02 53.41 8.8 ng/ml, 0.001). This increase (negatively HOMA value insulin, r -0.42, 0.02 -0.45, 0.01, respectively) decreased -0.54, As previously described adiponectin, improvement sensitivity.
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Kurt Widhalm, Renate Pakosta, Precipitation with polyethylene glycol and density-gradient ultracentrifugation compared for determining high-density lipoprotein subclasses HDL2 and HDL3. Clinical Chemistry. ,vol. 37, pp. 238- 240 ,(1991) , 10.1093/CLINCHEM/37.2.238
J N Fain, H S Sacks, B Buehrer, S W Bahouth, E Garrett, R Y Wolf, R A Carter, D S Tichansky, A K Madan, Identification of omentin mRNA in human epicardial adipose tissue: comparison to omentin in subcutaneous, internal mammary artery periadventitial and visceral abdominal depots. International Journal of Obesity. ,vol. 32, pp. 810- 815 ,(2008) , 10.1038/SJ.IJO.0803790
A Belza, S Toubro, S Stender, A Astrup, Effect of diet-induced energy deficit and body fat reduction on high-sensitive CRP and other inflammatory markers in obese subjects International Journal of Obesity. ,vol. 33, pp. 456- 464 ,(2009) , 10.1038/IJO.2009.27
Neda Rasouli, Philip A. Kern, Adipocytokines and the metabolic complications of obesity. The Journal of Clinical Endocrinology and Metabolism. ,vol. 93, ,(2008) , 10.1210/JC.2008-1613
A. Schäffler, M. Neumeier, H. Herfarth, A. Fürst, J. Schölmerich, C. Büchler, Genomic structure of human omentin, a new adipocytokine expressed in omental adipose tissue. Biochimica et Biophysica Acta. ,vol. 1732, pp. 96- 102 ,(2005) , 10.1016/J.BBAEXP.2005.11.005
M.V. Heinonen, D.E. Laaksonen, T. Karhu, L. Karhunen, T. Laitinen, S. Kainulainen, A. Rissanen, L. Niskanen, K.H. Herzig, Effect of diet-induced weight loss on plasma apelin and cytokine levels in individuals with the metabolic syndrome Nutrition Metabolism and Cardiovascular Diseases. ,vol. 19, pp. 626- 633 ,(2009) , 10.1016/J.NUMECD.2008.12.008
B. K. Tan, R. Adya, S. Farhatullah, K. C. Lewandowski, P. O'Hare, H. Lehnert, H. S. Randeva, Omentin-1, a novel adipokine, is decreased in overweight insulin-resistant women with polycystic ovary syndrome: ex vivo and in vivo regulation of omentin-1 by insulin and glucose. Diabetes. ,vol. 57, pp. 801- 808 ,(2008) , 10.2337/DB07-0990
C. M. de Souza Batista, R.-Z. Yang, M.-J. Lee, N. M. Glynn, D.-Z. Yu, J. Pray, K. Ndubuizu, S. Patil, A. Schwartz, M. Kligman, S. K. Fried, D.-W. Gong, A. R. Shuldiner, T. I. Pollin, J. C. McLenithan, Omentin Plasma Levels and Gene Expression Are Decreased in Obesity Diabetes. ,vol. 56, pp. 1655- 1661 ,(2007) , 10.2337/DB06-1506
Michael J. Puglisi, Maria Luz Fernandez, Modulation of C-Reactive Protein, Tumor Necrosis Factor-α, and Adiponectin by Diet, Exercise, and Weight Loss Journal of Nutrition. ,vol. 138, pp. 2293- 2296 ,(2008) , 10.3945/JN.108.097188
Javier Gómez-Ambrosi, Victoria Catalán, Beatriz Ramírez, Amaia Rodríguez, Inmaculada Colina, Camilo Silva, Fernando Rotellar, Carmen Mugueta, María J. Gil, Javier A. Cienfuegos, Javier Salvador, Gema Frühbeck, Plasma osteopontin levels and expression in adipose tissue are increased in obesity. The Journal of Clinical Endocrinology and Metabolism. ,vol. 92, pp. 3719- 3727 ,(2007) , 10.1210/JC.2007-0349