Intracranial hypertension: what additional information can be derived from ICP waveform after head injury?

摘要: Objective. Although intracranial hypertension is one of the important prognostic factors after head injury, increased pressure (ICP) may also be observed in patients with favourable outcome. We have studied whether value ICP monitoring can augmented by indices describing cerebrovascular pressure-reactivity and pressure-volume compensatory reserve derived from arterial blood (ABP) waveforms. Method. 96 were retrospectively: 57 fatal outcome 39 ABP waveforms recorded. Indices reactivity (PRx) cerebrospinal (RAP) calculated as moving correlation coefficients between slow waves ICP, pulse amplitude mean respectively. The magnitude ‘slow waves’ was using low-pass spectral filtration. Results. most significant difference found that persistently higher a (p<0.00004). In who died significantly (p<0.0001) (described PRx) compromised (p<0.024). same patients, showed gradual deterioration over time sudden drop RAP when started to rise, suggesting an overlapping disruption vasomotor response. Conclusion. waveform analysis helpful for interpretation progressive brain trauma.