Bimanual Coordination in Chronic Schizophrenia

摘要: Anomalies of movement are observed both clinically and experimentally in schizophrenia. While the basal ganglia have been implicated its pathogenesis, nature such involvement is equivocal. The may be involved bimanual coordination through their input to supplementary motor area (SMA). a neglected study schizophrenia, task provide means assessing functional integrity circuit. Twelve patients with chronic schizophrenia 12 matched control participants performed on set vertically mounted cranks at different speeds (1 2 Hz) phase relationships. Participants in-phase movements (hands separated by 0 degrees ) out-of-phase 180 an external cue or off. All well, irrespective speed cueing conditions. Patients were unable perform movements, particularly faster speed, reverting instead movement. There was no effect any These results suggest specific problem indicative SMA dysfunction per se and/or faulty callosal integration. A disturbance ability switch attention during also involved.