The West Nile Virus Outbreak of 1999 in New York: The Flushing Hospital Experience

摘要: West Nile Virus (WNV) is a mosquito-borne flavivirus, which has been known to cause human infection in Africa, the Middle East, and southwestern Asia. It also isolated Australia sporadically Europe but never Americas. Clinical features include acute fever, severe myalgias, headache, conjunctivitis, lymphadenopathy, roseolar rash. Rarely encephalitis or meningitis seen. During month of August 1999, cluster 5 patients with confusion, weakness were admitted intensive care unit same hospital New York City. Ultimately 4 developed flaccid paralysis required ventilatory support. Three less-severe cases presented shortly thereafter. With assistance City State health departments Centers for Disease Control Prevention, these documented as first WNV on this continent.