Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export

作者: Divyang Jani , Sheila Lutz , Ed Hurt , Ronald A. Laskey , Murray Stewart

DOI: 10.1093/NAR/GKS059

关键词:

摘要: … Mammalian TREX-2 is based on a germinal-centre associated nuclear protein (GANP) scaffold to which ENY2, PCID2 and centrins bind and depletion of any of these components …

参考文章(39)
Tamás Fischer, Katja Sträßer, Attila Rácz, Susana Rodriguez‐Navarro, Marisa Oppizzi, Petra Ihrig, Johannes Lechner, Ed Hurt, The mRNA export machinery requires the novel Sac3p-Thp1p complex to dock at the nucleoplasmic entrance of the nuclear pores The EMBO Journal. ,vol. 21, pp. 5843- 5852 ,(2002) , 10.1093/EMBOJ/CDF590
Tamás Fischer, Susana Rodríguez-Navarro, Gislene Pereira, Attila Rácz, Elmar Schiebel, Ed Hurt, Yeast centrin Cdc31 is linked to the nuclear mRNA export machinery Nature Cell Biology. ,vol. 6, pp. 840- 848 ,(2004) , 10.1038/NCB1163
James R. Thompson, Zachary C. Ryan, Jeffrey L. Salisbury, Rajiv Kumar, The structure of the human centrin 2-xeroderma pigmentosum group C protein complex. Journal of Biological Chemistry. ,vol. 281, pp. 18746- 18752 ,(2006) , 10.1074/JBC.M513667200
Yoshinori Takei, Magdalena Assenberg, Gozoh Tsujimoto, Ronald Laskey, The MCM3 acetylase MCM3AP inhibits initiation, but not elongation, of DNA replication via interaction with MCM3. Journal of Biological Chemistry. ,vol. 277, pp. 43121- 43125 ,(2002) , 10.1074/JBC.C200442200
Vihandha O. Wickramasinghe, Paul I.A. McMurtrie, Jackie Marr, Yoko Amagase, Sarah Main, Anthony D. Mills, Ronald A. Laskey, Yoshinori Takei, MCM3AP Is Transcribed from a Promoter within an Intron of the Overlapping Gene for GANP Journal of Molecular Biology. ,vol. 406, pp. 355- 361 ,(2011) , 10.1016/J.JMB.2010.12.035
Satoru Fujimura, Yan Xing, Motohiro Takeya, Yasuyuki Yamashita, Koichi Ohshima, Kazuhiko Kuwahara, Nobuo Sakaguchi, Increased Expression of Germinal Center–Associated Nuclear Protein RNA-Primase Is Associated with Lymphomagenesis Cancer Research. ,vol. 65, pp. 5925- 5934 ,(2005) , 10.1158/0008-5472.CAN-04-3259
Ghislain G. Cabal, Auguste Genovesio, Susana Rodriguez-Navarro, Christophe Zimmer, Olivier Gadal, Annick Lesne, Henri Buc, Frank Feuerbach-Fournier, Jean-Christophe Olivo-Marin, Eduard C. Hurt, Ulf Nehrbass, SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope Nature. ,vol. 441, pp. 770- 773 ,(2006) , 10.1038/NATURE04752
G. Hu, J. Kim, Q. Xu, Y. Leng, S. H. Orkin, S. J. Elledge, A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal Genes & Development. ,vol. 23, pp. 837- 848 ,(2009) , 10.1101/GAD.1769609
Susana Rodríguez-Navarro, Ed Hurt, Linking gene regulation to mRNA production and export. Current Opinion in Cell Biology. ,vol. 23, pp. 302- 309 ,(2011) , 10.1016/J.CEB.2010.12.002
S. R. Carmody, S. R. Wente, mRNA nuclear export at a glance Journal of Cell Science. ,vol. 122, pp. 1933- 1937 ,(2009) , 10.1242/JCS.041236