Preparation and Characterization of Polyurethane Porous Membranes by Particulate-leaching Method
作者： Salvatore Iannace , Ernesto Di Maio , Luigi Nicolais
DOI: 10.1177/026248930102000502
关键词:
摘要: Highly porous polyurethane foams were prepared by the particulate-leaching technique, using NaCI as water-soluble solid phase. Melt compounding and compression moulding used to prepare polymer/salt composite samples. Foams with controlled porosity, surface/volume ratio pore dimension distribution therefore obtained after dissolution of salt in distilled water. Dissolution kinetic was evaluated modelled a function filler composition its size distribution. Kinetic increased rising concentration reducing average size. Mechanical properties correlated their morphological structure polymeric component.
sagepub.com 
sci-hub.se 参考文章(23)
Steven T. Boyce, Skin Repair with Cultured Cells and Biopolymers Human Biomaterials Applications. pp. 347- 377 ,(1996) , 10.1007/978-1-4757-2487-5_15
Isidoro Caraballo, Mónica Millán, Adamo Fini, Lorenzo Rodriguez, Cristina Cavallari, Percolation thresholds in ultrasound compacted tablets Journal of Controlled Release. ,vol. 69, pp. 345- 355 ,(2000) , 10.1016/S0168-3659(00)00307-2
Susan L. Ishaug-Riley, Genevieve M. Crane-Kruger, Michael J. Yaszemski, Antonios G. Mikos, Three-dimensional culture of rat calvarial osteoblasts in porous biodegradable polymers. Biomaterials. ,vol. 19, pp. 1405- 1412 ,(1998) , 10.1016/S0142-9612(98)00021-0
H. Lo, M.S. Ponticiello, K.W. Leong, Fabrication of controlled release biodegradable foams by phase separation. Tissue Engineering. ,vol. 1, pp. 15- 28 ,(1995) , 10.1089/TEN.1995.1.15
Eva S. Miller, Nikolaos A. Peppas, Douglas N. Winslow, Morphological changes of ethylene/vinyl acetate-based controlled delivery systems during release of water-soluble solutes Journal of Membrane Science. ,vol. 14, pp. 79- 92 ,(1983) , 10.1016/S0376-7388(00)81375-7
Giacomo Di Colo, Controlled drug release from implantable matrices based on hydrophobia polymers Biomaterials. ,vol. 13, pp. 850- 856 ,(1992) , 10.1016/0142-9612(92)90178-Q
Ronald A. Siegel, Robert Langer, Mechanistic studies of macromolecular drug release from macroporous polymers. II. Models for the slow kinetics of drug release Journal of Controlled Release. ,vol. 14, pp. 153- 167 ,(1990) , 10.1016/0168-3659(90)90152-J
Takeru Higuchi, Rate of release of medicaments from ointment bases containing drugs in suspension Journal of Pharmaceutical Sciences. ,vol. 50, pp. 874- 875 ,(1961) , 10.1002/JPS.2600501018
M. Fabbri, G.C. Celotti, A. Ravaglioli, Hydroxyapatite-based porous aggregates : physico-chemical nature, structure, texture and architecture Biomaterials. ,vol. 16, pp. 225- 228 ,(1995) , 10.1016/0142-9612(95)92121-L
Ronald A. Siegel, Joseph Kost, Robert Langer, Mechanistic studies of macromolecular drug release from macroporous polymers. I. Experiments and preliminary theory concerning completeness of drug release Journal of Controlled Release. ,vol. 8, pp. 223- 236 ,(1989) , 10.1016/0168-3659(89)90044-8