Serum uric acid and hypertension : the Olivetti heart study

摘要: The association between serum uric acid and hypertension was evaluated in a sample of male workers southern Italy enrolled the Olivetti Heart Study, an ongoing longitudinal epidemiological investigation on risk factors for coronary heart disease carried out at factory suburban area Naples. Participants were screened baseline (1975) five year (1980) 12 (1987) follow-up examinations. present report focuses 619 whom information available both examination. At baseline, after excluding hypertensive participants (systolic blood pressure (SBP) > or = 140 mmHg and/or diastolic (DBP), 90 antihypertensive therapy; n 72), positively significantly related to age, SBP, DBP, body mass index (BMI), total cholesterol (CHOL) triglycerides (TG) 547 normotensive participants. examination, defined by SBP DBP being therapy. Multiple logistic regression analysis showed independent positive levels development (RR 1.23, 95% CI 1.07-1.39; p 0.011) adjustment BMI, CHOL TG. Furthermore, according more severe degrees (SBP 160 95 therapy), relative develop still significant 1.19; 1.01-1.38; 0.051).(ABSTRACT TRUNCATED AT 250 WORDS)