Hidradenitis suppurativa: A comprehensive review

摘要: Hidradenitis suppurativa, also known as acne inversa, is a chronic, often debilitating disease primarily affecting the axillae, perineum, and inframammary regions. Prevalence rates of up to 4% have been estimated. Our understanding has changed over time. It now considered follicular occlusion rather than an inflammatory or infectious process apocrine glands. Clinically, presents with tender subcutaneous nodules beginning around puberty. The may spontaneously rupture coalesce, forming painful, deep dermal abscesses. Eventually, fibrosis formation extensive sinus tracts result. location lesions lead social embarrassment failure seek medical treatment. Therapies in past consisted long-term antibiotics, antiandrogens, surgery. New treatments like tumor necrosis factor-alfa inhibitors given clinicians more options against this difficult disease.