The Langerhans cell: an underestimated cell in atopic disease

作者: W. J. FOKKENS , C. A. F. M. BRUIJNZEEL-KOOMEN , TH. M. VROOM , E. RIJNTJES , E. C. M. HOEFSMIT

DOI: 10.1111/J.1365-2222.1990.TB02701.X

关键词:

摘要: Langerhans cells (LC) are very potent antigen-presenting cells. In atopic disorders such as allergic rhinitis and dermatitis LC known to bear IgE surface molecules. IgE-positive can bind allergen present it T lymphocytes induce an allergen-specific T-cell response synthesis. Therefore, IgE-bearing might play important role in the triggering of immune system maintain ongoing The importance atopy has not been assessed but deserves further investigation find out more about part played by these cells, only described here also others gastrointestinal allergy asthma.

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