Prostate visualization studies in males homozygous and heterozygous for 5 alpha-reductase deficiency.

摘要: Male pseudohermaphrodites with 5 alpha-reductase deficiency have ambiguous genitalia and nonpalpable prostates on rectal examination, suggesting the dihydrotestosterone dependency of these structures. To clearly delineate status prostate, male had transrectal sonography prostate performed, results were compared to that age-matched controls. In six pseudohermaphrodites, magnetic resonance imaging studies also performed. Heterozygote fathers performed The appeared as platelike soft tissue structures posterior urethra both prostatic ultrasound imaging. Prostatic volume, determined by two different methods, was significantly smaller (approximately one-tenth) than volume ...