Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography Is Useless for the Detection of Local Recurrence after Radical Prostatectomy
作者： C. Hofer , C. Laubenbacher , T. Block , J. Breul , R. Hartung
DOI: 10.1159/000019923
关键词:
摘要: Objective: After radical retropubic prostatectomy a rise of the prostate-specific antigen (PSA) indicates local recurrent or metastatic disease. If bone scan shows no apparent metastasis, morphological imaging methods like x-ray computed tomography, magnetic resonance transrectal ultrasound often cannot distinguish between postoperative scar and recurrence. Therefore we investigated feasibility fluorine-18-fluorodeoxyglucose positron emission tomography (F-18 FDG PET) for metabolic characterization prostatic cancer, especially differentiation prostate cancer after prostatectomy. Methods: Dynamic PET with 370 MBq F-18 deoxyglucose FDG) up to 60 min p.i. was performed in 2 patients biopsy-proven benign hyperplasia, 11 histologically proven prior (RRP) 7 suspected recurrence (with negative scan) RRP biopsy anastomosis (3 recurrence, 4 scar). Results: Prostate showed very low uptake. The placement regions interest only possible by use other methods. There not difference uptake carcinoma, Conclusion: seems be useful
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