The effect of thalidomide on neovascularization in a mouse model of retinopathy of prematurity.

作者: Ronen Rabinowitz , Gabriel Katz , Mordechai Rosner , Sara Pri-Chen , Abraham Spierer

DOI: 10.1007/S00417-008-0781-Z

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摘要: Purpose Abnormal angiogenesis is the hallmark feature of retinopathy prematurity (ROP), and contributes to severe visual loss that accompanies this disease. Thalidomide a well-known anti-angiogenic drug. We tested assumption injection intraperitoneal thalidomide could reduce severity oxygen-induced (OIR) in mouse model.

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