Beyond mRNA: The role of non-coding RNAs in normal and aberrant hematopoiesis
作者： Mark C. Wilkes , Claire E. Repellin , Kathleen M. Sakamoto
DOI: 10.1016/J.YMGME.2017.07.008
关键词:
摘要: The role of non-coding Ribonucleic Acids (ncRNAs) in biology is currently an area intense focus. Hematopoiesis requires rapidly changing regulatory molecules to guide appropriate differentiation and ncRNA are well suited for this. It not surprising that virtually all aspects hematopoiesis have roles ncRNAs assigned them doubtlessly much more await characterization. Stem cell maintenance, lymphoid, myeloid erythroid regulated by various ncRNAs, including microRNAs (miRNAs), long RNAs (lncRNAs) transposable elements within the genome. As our understanding many complex continues grow, new discoveries challenging existing classification schemes. In this review we briefly overview broad categories discuss a few examples regulating normal aberrant hematopoiesis.
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