Effect of Dietary Restriction on Muscle Performance in Drosophila

摘要: Dietary restriction (DR) can extend the lifespan in various organisms and is thought to present potential benefits human. However, it still a controversial issue now among scientists due lack of strong supportive evidence Aging an important every developed country, aging process causes neurodegeneration sarcopenia, (the degeneration muscle mass, strength function). The aim was understand sarcopenia model organism, Drosophila melanogaster, by monitoring decline output single twitch muscle, jump with age. Jumping assays were performed using ergometer, while flies fed different yeast concentrations throughout their adult life. We did not observe failure neuronal conduction as aged; rather performance declined gradually Flies reduced concentration showed significant extension both Canton-S or Canton-S/Wee-P but no difference jumping performance. raised high from larval stage had shorter without any