Cystic Disease in Women: Clinical Characteristics and Medical Management

摘要: Autosomal dominant polycystic kidney disease (ADPKD) is a dominantly inherited systemic disorder equally in men and women characterized by renal cyst development expansion ultimately leading to failure. ADPKD have slower rate of progression failure, with later age entry into end·stage (ESRD) as compared men. Renal growth are the hallmarks ADPKD, will develop insufficiency smaller volume than their male counterparts. As well, different rates occurrence extrarenal complications ADPKD. related including hypertension gross hematuria, occur more frequently women, whereas liver cystic occurs earlier The presence pregnancy number oral contraceptive pill use women. Importantly, massive requiring surgical intervention primarily ADKPD highly successful reproductive course. chance excellent comparable healthy unaffected long prepregnancy blood pressure function normal. Fetal complication no greater general population; however, maternal high an increased frequency new or worsening well preeclampsia preterm deliveries. Finally, increasing has minimal effect on outcome