Bacterial Metabolism, Fiber, and Colorectal Cancer

摘要: A role for dietary fiber in colorectal carcinogenesis was proposed by Burkitt (1969, 1970, 1971). He that the mechanism which this occurred caused: 1. Stool bulking and consequent dilution of colonic contents, including carcinogens tumor promoters present lumen. 2. A faster rate transit through colon, decreasing time available situ production carcinogens, promoters, etc. bacterial action. 3. A change flora colon to one would be less likely produce etc. 4. A physicochemical environment favorable