Metabolites as Intercellular Signals for Regulation of Community-Level Traits
作者： Russell D. Monds , George A. O'Toole
DOI: 10.1128/9781555815578.CH8
关键词:
摘要: This chapter describes work on new and emerging systems that describe roles for excreted cellular metabolites as intercellular signals. The therapeutic value of antibiotics is unquestionable; however, understanding the biological role these compounds in natural settings may not be intuitive definition would suggest. Increases biofilm formation were correlated with a 10-fold increase expression ica operon upon treatment antibiotic. internal concentration polyamines tightly regulated through combination biosynthesis, transport, excretion. In Escherichia coli, putrescine synthesized either by decarboxylation L-ornithine or Larginine followed removal urea molecule. P. aeruginosa known to make excrete both monorhamnolipids (mono-RHLs) dirhamnolipids (di-RHLs), which have one two attached rhamnose groups, respectively. E. indole imported from extracellular environment predominantly Mtr permease whereas efflux out cell performed AcrEF pump. provides evidence supports various regulation community-level traits, such formation, swarming, filamentation.
asmscience.org参考文章(105)
Elizabeth M. Boon, Joseph H. Davis, Rosalie Tran, David S. Karow, Shirley H. Huang, Duohai Pan, Michael M. Miazgowicz, Richard A. Mathies, Michael A. Marletta, Nitric Oxide Binding to Prokaryotic Homologs of the Soluble Guanylate Cyclase β1 H-NOX Domain Journal of Biological Chemistry. ,vol. 281, pp. 21892- 21902 ,(2006) , 10.1074/JBC.M600557200
M. G. Surette, M. B. Miller, B. L. Bassler, Quorum sensing in Escherichia coli, Salmonella typhimurium, and Vibrio harveyi: A new family of genes responsible for autoinducer production Proceedings of the National Academy of Sciences of the United States of America. ,vol. 96, pp. 1639- 1644 ,(1999) , 10.1073/PNAS.96.4.1639
Jyoti Shah, The salicylic acid loop in plant defense. Current Opinion in Plant Biology. ,vol. 6, pp. 365- 371 ,(2003) , 10.1016/S1369-5266(03)00058-X
Natividad Ruiz, Thomas J Silhavy, Sensing external stress: watchdogs of the Escherichia coli cell envelope. Current Opinion in Microbiology. ,vol. 8, pp. 122- 126 ,(2005) , 10.1016/J.MIB.2005.02.013
Gee W. Lau, Daniel J. Hassett, Huimin Ran, Fansheng Kong, The role of pyocyanin in Pseudomonas aeruginosa infection Trends in Molecular Medicine. ,vol. 10, pp. 599- 606 ,(2004) , 10.1016/J.MOLMED.2004.10.002
Corinne Dorel, Philippe Lejeune, Agnès Rodrigue, The Cpx system of Escherichia coli, a strategic signaling pathway for confronting adverse conditions and for settling biofilm communities? Research in Microbiology. ,vol. 157, pp. 306- 314 ,(2006) , 10.1016/J.RESMIC.2005.12.003
Hiten D Madhani, Gerald R Fink, The control of filamentous differentiation and virulence in fungi Trends in Cell Biology. ,vol. 8, pp. 348- 353 ,(1998) , 10.1016/S0962-8924(98)01298-7
R. R. Baca-DeLancey, M. M. T. South, X. Ding, P. N. Rather, Escherichia coli genes regulated by cell-to-cell signaling. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 96, pp. 4610- 4614 ,(1999) , 10.1073/PNAS.96.8.4610
Eleanor L. Chant, David K. Summers, Indole signalling contributes to the stable maintenance of Escherichia coli multicopy plasmids Molecular Microbiology. ,vol. 63, pp. 35- 43 ,(2007) , 10.1111/J.1365-2958.2006.05481.X
J. F. Linares, I. Gustafsson, F. Baquero, J. L. Martinez, Antibiotics as intermicrobial signaling agents instead of weapons Proceedings of the National Academy of Sciences of the United States of America. ,vol. 103, pp. 19484- 19489 ,(2006) , 10.1073/PNAS.0608949103