Pathophysiological Roles of Chemokines in Human Reproduction: An Overview

作者: Kotaro Kitaya , Hisao Yamada

DOI: 10.1111/J.1600-0897.2010.00928.X

关键词:

摘要: Chemokines are a group of small cytokines that have an ability to induce leukocyte migration. exert their functions by binding and activating specific G protein-coupled receptors. Studies unveiled pleiotropic bioactivities chemokines in various phenomena ranging from immunomodulation, embryogenesis, homeostasis pathogenesis. In the mammalian reproductive system, unexceptionally serve multimodal events closely associated with establishment, maintenance, deterioration fecundity. The aim this review is update knowledge on male female genital organs, focus potential pathophysiological roles human reproduction.

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