Intraoperative treatment strategy to reduce the incidence of postcardiopulmonary bypass atrial fibrillation

摘要: Purpose: Postcardiopulmonary bypass atrial fibrillation remains a constant complication associated with coronary revascularization, the incidence of which occurs from 20% to 35%. Previous studies have addressed this problem in postoperative setting utilizing pharmacological agents, but results been variable. The purpose study was evaluate novel intraoperative strategy reduce postcardiopulmonary fibrillation. We theorized that leukocyte depletion by filtration addition aprotinin would systemic inflammatory effects and fibrillation.Methods: One hundred twenty-two patients participated randomized study. Only isolated primary revascularization procedures on cardiopulmonary were included. control group (n= 55) received standard moderate hypothermic blood cardioplegia bypass. treatment 65) similar bypass...