Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

James R Downing, Richard K Wilson, Jinghui Zhang, Elaine R Mardis, Ching-Hon Pui, Li Ding, Timothy J Ley, William E Evans, None, The Pediatric Cancer Genome Project Nature Genetics. ,vol. 44, pp. 619- 622 ,(2012) , 10.1038/NG.2287

Giles Robinson, Matthew Parker, Tanya A. Kranenburg, Charles Lu, Xiang Chen, Li Ding, Timothy N. Phoenix, Erin Hedlund, Lei Wei, Xiaoyan Zhu, Nader Chalhoub, Suzanne J. Baker, Robert Huether, Richard Kriwacki, Natasha Curley, Radhika Thiruvenkatam, Jianmin Wang, Gang Wu, Michael Rusch, Xin Hong, Jared Becksfort, Pankaj Gupta, Jing Ma, John Easton, Bhavin Vadodaria, Arzu Onar-Thomas, Tong Lin, Shaoyi Li, Stanley Pounds, Steven Paugh, David Zhao, Daisuke Kawauchi, Martine F. Roussel, David Finkelstein, David W. Ellison, Ching C. Lau, Eric Bouffet, Tim Hassall, Sridharan Gururangan, Richard Cohn, Robert S. Fulton, Lucinda L. Fulton, David J. Dooling, Kerri Ochoa, Amar Gajjar, Elaine R. Mardis, Richard K. Wilson, James R. Downing, Jinghui Zhang, Richard J. Gilbertson, Novel mutations target distinct subgroups of medulloblastoma Nature. ,vol. 488, pp. 43- 48 ,(2012) , 10.1038/NATURE11213

Adam Naguib, Catherine H Wilson, David J Adams, Mark J Arends, Activation of K-RAS by co-mutation of codons 19 and 20 is transforming. Journal of Molecular Signaling. ,vol. 6, pp. 2- 2 ,(2011) , 10.1186/1750-2187-6-2

Trevor J. Pugh, Shyamal Dilhan Weeraratne, Tenley C. Archer, Daniel A. Pomeranz Krummel, Daniel Auclair, James Bochicchio, Mauricio O. Carneiro, Scott L. Carter, Kristian Cibulskis, Rachel L. Erlich, Heidi Greulich, Michael S. Lawrence, Niall J. Lennon, Aaron McKenna, James Meldrim, Alex H. Ramos, Michael G. Ross, Carsten Russ, Erica Shefler, Andrey Sivachenko, Brian Sogoloff, Petar Stojanov, Pablo Tamayo, Jill P. Mesirov, Vladimir Amani, Natalia Teider, Soma Sengupta, Jessica Pierre Francois, Paul A. Northcott, Michael D. Taylor, Furong Yu, Gerald R. Crabtree, Amanda G. Kautzman, Stacey B. Gabriel, Gad Getz, Natalie Jäger, David T. W. Jones, Peter Lichter, Stefan M. Pfister, Thomas M. Roberts, Matthew Meyerson, Scott L. Pomeroy, Yoon-Jae Cho, Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations Nature. ,vol. 488, pp. 106- 110 ,(2012) , 10.1038/NATURE11329

Philip J Stephens, Patrick S Tarpey, Helen Davies, Peter Van Loo, Chris Greenman, David C Wedge, Serena Nik-Zainal, Sancha Martin, Ignacio Varela, Graham R Bignell, Lucy R Yates, Elli Papaemmanuil, David Beare, Adam Butler, Angela Cheverton, John Gamble, Jonathan Hinton, Mingming Jia, Alagu Jayakumar, David Jones, Calli Latimer, King Wai Lau, Stuart McLaren, David J McBride, Andrew Menzies, Laura Mudie, Keiran Raine, Roland Rad, Michael Spencer Chapman, Jon Teague, Douglas Easton, Anita Langerød, Oslo Breast Cancer Consortium (OSBREAC) Karesen Rolf 34 35 Schlichting Ellen 34 Naume Bjorn 35 36 Sauer Torill 35 37 Ottestad Lars 36, Ming Ta Michael Lee, Chen-Yang Shen, Benita Tan Kiat Tee, Bernice Wong Huimin, Annegien Broeks, Ana Cristina Vargas, Gulisa Turashvili, John Martens, Aquila Fatima, Penelope Miron, Suet-Feung Chin, Gilles Thomas, Sandrine Boyault, Odette Mariani, Sunil R Lakhani, Marc van de Vijver, Laura van ‘t Veer, John Foekens, Christine Desmedt, Christos Sotiriou, Andrew Tutt, Carlos Caldas, Jorge S Reis-Filho, Samuel AJR Aparicio, Anne Vincent Salomon, Anne-Lise Børresen-Dale, Andrea L Richardson, Peter J Campbell, P Andrew Futreal, Michael R Stratton, None, The landscape of cancer genes and mutational processes in breast cancer Nature. ,vol. 486, pp. 400- 404 ,(2012) , 10.1038/NATURE11017

Karine Jacob, Dongh-Anh Quang-Khuong, David T.W. Jones, Hendrik Witt, Sally Lambert, Steffen Albrecht, Olaf Witt, Catherine Vezina, Margret Shirinian, Damien Faury, Miklos Garami, Peter Hauser, Almos Klekner, Laszlo Bognar, Jean-Pierre Farmer, Jose-Luis Montes, Jeffrey Atkinson, Cynthia Hawkins, Andrey Korshunov, V. Peter Collins, Stefan M. Pfister, Uri Tabori, Nada Jabado, Genetic aberrations leading to MAPK pathway activation mediate oncogene-induced senescence in sporadic pilocytic astrocytomas Clinical Cancer Research. ,vol. 17, pp. 4650- 4660 ,(2011) , 10.1158/1078-0432.CCR-11-0127

Chris L. Lannon, Poul H.B. Sorensen, ETV6-NTRK3: a chimeric protein tyrosine kinase with transformation activity in multiple cell lineages. Seminars in Cancer Biology. ,vol. 15, pp. 215- 223 ,(2005) , 10.1016/J.SEMCANCER.2005.01.003

K. Wang, M. Li, H. Hakonarson, ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data Nucleic Acids Research. ,vol. 38, ,(2010) , 10.1093/NAR/GKQ603

S. A. Forbes, N. Bindal, S. Bamford, C. Cole, C. Y. Kok, D. Beare, M. Jia, R. Shepherd, K. Leung, A. Menzies, J. W. Teague, P. J. Campbell, M. R. Stratton, P. A. Futreal, COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Research. ,vol. 39, pp. 945- 950 ,(2011) , 10.1093/NAR/GKQ929

Alexander Schramm, Johannes H. Schulte, Kathy Astrahantseff, Ognjan Apostolov, Vera van Limpt, Hauke Sieverts, Steffi Kuhfittig-Kulle, Petra Pfeiffer, Rogier Versteeg, Angelika Eggert, Biological effects of TrkA and TrkB receptor signaling in neuroblastoma Cancer Letters. ,vol. 228, pp. 143- 153 ,(2005) , 10.1016/J.CANLET.2005.02.051